USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: GSTO1_HUMAN USC-OGP 2-DE database:  GSTO1_HUMAN GSTO1_HUMAN General information about the entry View entry in simple text format Entry name GSTO1_HUMAN Primary accession number P78417 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Glutathione S-transferase omega-1; Short=GSTO-1; EC=2.5.1.18 {ECO:0000269|PubMed:10783391, ECO:0000269|PubMed:11511179, ECO:0000269|PubMed:17226937, ECO:0000269|PubMed:18028863, ECO:0000269|PubMed:21106529}; AltName: Full=Glutathione S-transferase omega 1-1; Short=GSTO 1-1; AltName: Full=Glutathione-dependent dehydroascorbate reductase; EC=1.8.5.1 {ECO:0000269|PubMed:10783391, ECO:0000269|PubMed:11511179}; AltName: Full=Monomethylarsonic acid reductase; Short=MMA(V) reductase; EC=1.20.4.2 {ECO:0000269|PubMed:11511179}; AltName: Full=S-(Phenacyl)glutathione reductase; Short=SPG-R;. Gene name Name=GSTO1 Synonyms=GSTTLP28 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0493: pI=5.58; Mw=29365 SPOT OGP-0494: pI=5.86; Mw=29262 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0770: pI=5.59; Mw=30520 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-1000: pI=5.74; Mw=27644 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1262: pI=6.11; Mw=29778 SPOT OGP-1263: pI=6.56; Mw=29778 Cross-references UniProtKB/Swiss-Prot P78417; GSTO1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GSTO1_HUMAN Primary accession number P78417 Secondary accession number(s) D3DRA3 F5H7H0 Q5TA03 Q7Z3T2 Sequence was last modified on  January 1, 1998 (version 2) Annotations were last modified on  March 15, 2017 (version 180) Name and origin of the protein Description RecName: Full=Glutathione S-transferase omega-1; Short=GSTO-1; EC=2.5.1.18 {ECO:0000269|PubMed:10783391, ECO:0000269|PubMed:11511179, ECO:0000269|PubMed:17226937, ECO:0000269|PubMed:18028863, ECO:0000269|PubMed:21106529}; AltName: Full=Glutathione S-transferase omega 1-1; Short=GSTO 1-1; AltName: Full=Glutathione-dependent dehydroascorbate reductase; EC=1.8.5.1 {ECO:0000269|PubMed:10783391, ECO:0000269|PubMed:11511179}; AltName: Full=Monomethylarsonic acid reductase; Short=MMA(V) reductase; EC=1.20.4.2 {ECO:0000269|PubMed:11511179}; AltName: Full=S-(Phenacyl)glutathione reductase; Short=SPG-R; Gene name Name=GSTO1 Synonyms=GSTTLP28 Encoded on Name=GSTO1; Synonyms=GSTTLP28 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U90313; AAB70109.1; -; mRNA EMBL AF212303; AAF73376.1; -; mRNA EMBL AY817669; AAV68046.1; -; Genomic_DNA EMBL BX537431; CAD97673.1; ALT_INIT; mRNA EMBL AL139341; CAI17224.1; -; Genomic_DNA EMBL CH471066; EAW49601.1; -; Genomic_DNA EMBL CH471066; EAW49602.1; -; Genomic_DNA EMBL CH471066; EAW49603.1; -; Genomic_DNA EMBL BC000127; AAH00127.1; -; mRNA CCDS CCDS53572.1; -. [P78417-2]; . CCDS CCDS53573.1; -. [P78417-3]; . CCDS CCDS7555.1; -. [P78417-1]; . RefSeq NP_001177931.1; NM_001191002.1. [P78417-2]; . RefSeq NP_001177932.1; NM_001191003.1. [P78417-3]; . RefSeq NP_004823.1; NM_004832.2. [P78417-1]; . UniGene Hs.190028; -; . PDB 1EEM; X-ray; 2.00 A; A=1-241 PDB 3LFL; X-ray; 2.10 A; A/B/C=1-241 PDB 3VLN; X-ray; 1.70 A; A=1-241 PDB 4IS0; X-ray; 1.72 A; A=1-241 PDB 4YQM; X-ray; 2.38 A; A/B/C=1-241 PDB 4YQU; X-ray; 1.94 A; A/B=1-241 PDB 4YQV; X-ray; 2.06 A; A/B/C=1-241 PDBsum 1EEM; -; . PDBsum 3LFL; -; . PDBsum 3VLN; -; . PDBsum 4IS0; -; . PDBsum 4YQM; -; . PDBsum 4YQU; -; . PDBsum 4YQV; -; . ProteinModelPortal P78417; -; . SMR P78417; -; . BioGrid 114836; 35; . IntAct P78417; 8; . MINT MINT-1384709; -; . STRING 9606.ENSP00000358727; -; . BindingDB P78417; -; . ChEMBL CHEMBL3174; -; . DrugBank DB00143; Glutathione; . DrugBank DB00163; Vitamin E; . iPTMnet P78417; -; . PhosphoSitePlus P78417; -; . SwissPalm P78417; -; . BioMuta GSTO1; -; . DMDM 6016173; -; . OGP P78417; -; . UCD-2DPAGE P78417; -; . EPD P78417; -; . PaxDb P78417; -; . PeptideAtlas P78417; -; . PRIDE P78417; -; . TopDownProteomics P78417-1; -. [P78417-1]; . Ensembl ENST00000369710; ENSP00000358724; ENSG00000148834. [P78417-2]; . Ensembl ENST00000369713; ENSP00000358727; ENSG00000148834. [P78417-1]; . Ensembl ENST00000539281; ENSP00000441488; ENSG00000148834. [P78417-3]; . GeneID 9446; -; . KEGG hsa:9446; -; . UCSC uc021pxr.2; human. [P78417-1]; . CTD 9446; -; . DisGeNET 9446; -; . GeneCards GSTO1; -; . HGNC HGNC:13312; GSTO1; . HPA HPA037603; -; . HPA HPA037604; -; . MIM 605482; gene; . neXtProt NX_P78417; -; . OpenTargets ENSG00000148834; -; . PharmGKB PA133787054; -; . eggNOG KOG0406; Eukaryota; . eggNOG ENOG410XSIX; LUCA; . GeneTree ENSGT00390000005479; -; . HOGENOM HOG000006560; -; . HOVERGEN HBG051853; -; . InParanoid P78417; -; . KO K00799; -; . OMA STITCEY; -; . OrthoDB EOG091G0IEA; -; . PhylomeDB P78417; -; . TreeFam TF105325; -; . BioCyc MetaCyc:HS07564-MONOMER; -; . BRENDA 1.20.4.2; 2681; . BRENDA 1.8.5.1; 2681; . BRENDA 2.5.1.18; 2681; . Reactome R-HSA-156581; Methylation; . Reactome R-HSA-156590; Glutathione conjugation; . Reactome R-HSA-196836; Vitamin C (ascorbate) metabolism; . ChiTaRS GSTO1; human; . EvolutionaryTrace P78417; -; . GeneWiki GSTO1; -; . GenomeRNAi 9446; -; . PRO PR:P78417; -; . Proteomes UP000005640; Chromosome 10; . Bgee ENSG00000148834; -; . CleanEx HS_GSTO1; -; . ExpressionAtlas P78417; baseline and differential; . Genevisible P78417; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0045174; F:glutathione dehydrogenase (ascorbate) activity; IDA:UniProtKB; . GO GO:0004364; F:glutathione transferase activity; IDA:UniProtKB; . GO GO:0050610; F:methylarsonate reductase activity; TAS:Reactome; . GO GO:0016491; F:oxidoreductase activity; IDA:UniProtKB; . GO GO:0071243; P:cellular response to arsenic-containing substance; IDA:UniProtKB; . GO GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome; . GO GO:0019852; P:L-ascorbic acid metabolic process; IDA:UniProtKB; . GO GO:0032259; P:methylation; TAS:Reactome; . GO GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL; . GO GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL; . GO GO:0014810; P:positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; IC:BHF-UCL; . GO GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IC:BHF-UCL; . GO GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:BHF-UCL; . GO GO:0042178; P:xenobiotic catabolic process; IDA:UniProtKB; . Gene3D 1.20.1050.10; -; 1; . Gene3D 3.40.30.10; -; 1; . InterPro IPR010987; Glutathione-S-Trfase_C-like; . InterPro IPR004045; Glutathione_S-Trfase_N; . InterPro IPR004046; GST_C; . InterPro IPR005442; GST_omega; . InterPro IPR012336; Thioredoxin-like_fold; . Pfam PF14497; GST_C_3; 1; . Pfam PF13417; GST_N_3; 1; . PRINTS PR01625; GSTRNSFRASEO; . SUPFAM SSF47616; SSF47616; 1; . SUPFAM SSF52833; SSF52833; 1; . PROSITE PS50405; GST_CTER; 1; . PROSITE PS50404; GST_NTER; 1; .

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